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Description

This can possibly be explained by a hormonally lowered neuro-excitability threshold for these headache attacks 68

CoQ 10 is synthesized endogenously from amino acids (tyrosine/phenylalanine) and via the mevalonate pathway with vitamin cofactors, and while meat and fish are the richest dietary sources, it is also present in plant-based foods such as vegetable oils, nuts, and whole grains [123,124,125,126]

doi: 10.3390/nu14010057

Initial management focuses on lifestyle modifications, including dietary changes, weight loss, and regular aerobic exercise, which directly improve peripheral insulin sensitivity

Within the nucleus, Nrf2 heterodimerizes with small Maf proteins and binds to cis-regulatory DNA sequences termed Antioxidant Response Elements (AREs)