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Case-fatality rates for RMSF were as high as 6580% prior to antibiotics 3 and can be fatal even after antibiotic treatment 4

Since the formation of stable metal-thiolate complexes precludes the direct thiol-disulfide redox potential measurements by usual electrochemical techniques, an indirect method had to be elaborated

Although no GLO1 inhibitor has yet been developed that has potential for use in therapy, mainly due to adverse side effects [261], exogenous application of MGO to further increase aldehyde stress has shown promising effects in a mouse model [262]

GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites

doi: 10.1161/ATVBAHA.124.321201

In vivo imaging of glutamine metabolism to the oncometabolite 2-hydroxyglutarate in IDH1/2 mutant tumors
