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Phase 3 monotherapy available Feature Expected GI burden Cagrilintide + Retatrutide Very high CagriSema (Cag + Sema) High Retatrutide Alone High Feature Dysesthesia risk Cagrilintide + Retatrutide Yes (retatrutide component) CagriSema (Cag + Sema) No Retatrutide Alone Yes Feature Injections per week Cagrilintide + Retatrutide 2 (separate) or 1 (pre-blend) CagriSema (Cag + Sema) 1 or 2 Retatrutide Alone 1 Feature Regulatory status Cagrilintide + Retatrutide Neither approved

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Systemic tissue support

CagriSema versus semaglutide or cagrilintide in people with type 2 diabetes (REIMAGINE 2): a randomised, controlled, phase 3 study

2 02:51 Writer: Kzino / Composers: Kzino / Other contributors: D.R 05 Ou diferan, pt

If she didnt agree to sign within one day, Johnson told her, the stock options were off the table