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Reduced sirtuin activity in an NAD + -depleted environment contributes, both indirectly via metabolic collapse and augmented fibrotic signaling, as well as by further inducing cellular senescence, to unchecked fibroblast activation and myofibroblast persistence driving intractable fibrosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Reversible hyperpigmentation in vitamin B12 deficiency: an Addisonian mimic in clinical practice

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