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By blocking NNMT, 5-Amino-1MQ preserves the NAD+ precursor pool and intracellular SAM (the universal methyl donor), effectively closing a metabolic drain that accelerates fat storage and cellular aging
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10.1111/j.0954-6820.1978.tb08402.x [DOI] [PubMed] 50.Berlin H, Berlin R, Brante G (1968) Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor