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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

Dabelea et al [18], found that among adolescents and young adults diagnosed with Type 1 or Type 2 diabetes during childhood or adolescence, the age-adjusted prevalence of peripheral neuropathy was higher in those with T2D than in patients with T1D (17.7% vs

The pharmacological basis of therapeutics

2016;17(1):p

VIP, variable importance in projection