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Higher levels of IL-10 and TGF- , as well as dendritic-derived B-cell activating factor (BAFF) and proliferation-inducing ligand (APRIL), also promote B regulatory (B reg ) cells differentiation into IgA-producing plasma cells [55]

According to data from the International Diabetes Federation, more than 382 million people around the world suffered from diabetes in 2013

Yi Zhou, MD3,7

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While the introductory overview touches on these, a more granular examination of the involved signaling cascades reveals a multi-pronged mechanism that researchers aim to exploit

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