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10.1016/j.toxlet.2004.06.009 46 McKnightR

The trial did not resume

Berberine suppresses neuroinflammatory responses through AMPactivated protein kinase activation in BV2 microglia

doi: 10.3389/fmed.2022.795762 Received 15 October 2021 Accepted 10 February 2022 Published 01 March 2022 Volume 9 - 2022 Edited by Beatrice Aramini, University Hospital of Modena, Italy Reviewed by Miroslava Matkov, Biomedical Research Center, Slovak Academy of Sciences, Slovakia

Because patients with hypertension exhibit persistent activation of inflammatory signaling and impaired resolution capacity, conventional antihypertensive drugs alone are insufficient to restore vascular function

We will be keeping our eyes peeled for when Defiant takes to the water for the first time later this year
