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Furthermore, exosome-derived circTRPS1 from bladder cancer (BCa) cells could regulate intracellular ROS homeostasis and promote CD8 T cell depletion via the circTRPS1/miR141-3p/GLS1 axis [99]

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Understanding these features may provide critical insights into novel therapeutic strategies aimed at targeting AML DTP cells, especially in the new era of immunotherapy against AML