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Bearden, S

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No significant changes in enzymatic activity of glutathione peroxidase (GSH-Px) (Figure 3F) were observed in testicular tissue

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Consistent with the importance of GSH in hepatic fibrogenesis, we found that a lower hepatic GSH level greatly potentiated BDL-induced fibrosis and if induction in GCLC expression was blocked (by using RNAi), the therapeutic efficacy of UDCA and SAMe was nearly lost [174]