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Dhonukshe-Rutten, R

Bromocriptine, the first dopamine receptor agonist, was originally made available in the 1970s, and has since grown in importance as a treatment for Parkinson's disease's motor symptoms

doi: 10.1016/j.freeradbiomed.2014.09.032

As used herein, "conditions which allow alkylation of the sulfhydryl group of GSH with the maleimide" typically require that the maleimide (such as NEM) is (initially) present at a concentration of at least 0.0001 mM, preferably at least 0.001 mM, more preferably at least 0.01 mM, even more preferably at least 0.1 mM, yet even more preferably at least 1 mM or even at least 2 mM

thus, neurons contain a large number of mitochondria