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PTC is the most common form and is characterized by relatively simple genetic mutations, which primarily activate signaling through the MAPK pathway [36], such as BRAFV600E (60%), RAS (15%), and gene fusions involving BRAF, RET, NTRK, and ALK (12%) [37]

Promising approaches include the pre-sowing seed priming technique, post-germination supplementary treatments, microbial biostimulation, and microRNA manipulation

Four of these biomarkers are components of the Neuroinflammation Signaling pathway, and four are components of the IL-17 Signaling pathway

Geronzi et al., 2018)

3.2.2 White matter lesions CKD has been associated with structural brain changes, particularly WMLs (75, 76)

Staff AC, Johnsen GM, Dechend R, Redman CWG (2014) Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factors