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Useful effects of cannabinoids in animals have been mentioned e.g., for disorders of the cardiovascular system, pain treatment, disorders of the respiratory system or metabolic disorders

However, after oxidative stimulation, the thiol groups of Keap1 undergo covalent modifications, causing its dissociation from Nrf2, which in turn translocates into the nucleus and promotes antioxidant enzyme expression by binding to Antioxidant Response Elements [98,99]
10.1016/j.cell.2020.03.043 30 HuberN.GuimaraesS.SchraderM.SuterU.NiemannA

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This is why working closely with a healthcare professional is crucial when considering glutathione supplementation or any other dietary supplement
