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The problem of spectral resolution and the validity of static whole tissue metabolite measurements has been partially addressed by increasing field strength, using spectral editing techniques that further resolve a peak of interest and functional 1 H-MRS with some limited improvement

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However, the overall bioavailability of each form of supplemental B 12 may be influenced by many factors such as gastrointestinal pathologies, age, and genetics
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doi: 10.1016/j.advnut.2023.05.005