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Under normal physiologic conditions, intracellular GSH concentrations of neurons are 250- to 500-fold higher than in the CSF, 17 thus limiting the utility of CSF to serve as a biomarker of cellular GSH status

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Kluge I, Gutteck-Amsler U, Zollinger M, Do K-Q

doi: 10.1016/j.neuroscience.2019.02.020

Eventually, ferroptosis accelerates the signs we associate with menopausal skin aging skin drying and thinning, poor healing, reduced radiance, and overall weakened skin barrier function