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Description
This function makes GPx4 the primary enzymatic barrier against ferroptosis, an iron-dependent form of regulated cell death driven by uncontrolled lipid peroxidation

Stacking amplifies side-effect risk with no proven added benefit

10.1074/jbc.M113.478545 49 KenslerT

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Hara KY, Kiriyama K, Inagaki A, Nakayama H, Kondo A (2012) Improvement of glutathione production by metabolic engineering the sulfate assimilation pathway of Saccharomyces cerevisiae
