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Take too high of a dose of melatonin and you could experience transient feelings of depression or anxiety

F.et al (2017)

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In the study of lung adenocarcinoma, high doses of -nicotinamide mononucleotide promote ferroptosis and inhibit lung cancer cell growth through the excess nicotinamide-mediated SIRT1/AMPK/acetyl-coA carboxylase (ACC) signaling pathway (Zhang et al., 2023a)

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A Synthetic ERR Agonist Induces an Acute Aerobic Exercise Program in Mice