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Potential anti-cancer properties of grape antioxidants

with malignant pleural mesothelioma (Mpm)

However, there is currently relatively little clinical research in this area, and further research is needed to confirm its efficacy and safety

A 2.5-year retrospective study from India suggests that intravenous edaravone treatment has no beneficial effect on the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALS-FRS) score and does not improve survival rate (33)

In fact, MPTP depletes kynurenic acid level (77)

Rg1 protects cells against apoptosis caused by MPTP by increasing Bcl-2 and Bcl-xl expression, decreasing Bax and iNOS expression and blocking caspase-3 activation (Chen et al., 2002)