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doi: 10.1001/jama.285.23.2981

1,2,3 Upon injury or stress, MuSCs activate, proliferate, and differentiate to repair damaged tissue while maintaining the stem cell pool through self-renewal

In the context of CHD, these processes contribute to the recruitment of inflammatory cells to the arterial wall, accelerate the progression of atherosclerotic plaques, and increase the risk of plaque rupture and subsequent cardiovascular events (125)

Unless specified, mice were housed at 22 C in groups of five

Method Enzymol 186, 448457 (1990)

The most common side effect associated with stimulation is hoarseness, voice alteration, increased cough, pharyngitis, dyspnea, dyspepsia, and nausea