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For more information on micronutrients and phytochemicals related to cognitive decline or neurodegenerative diseases, see the article on Micronutrients for Older Adults

[DOI] [PubMed] [Google Scholar] 148.OHagan S., Wright Muelas M., Day P.J., Lundberg E., Kell D.B

448 Moreover, energy demand changes dramatically when immune cells shift from a resting state to an active state, which often causes energy deficits when cells become senescent and, consequently, contributes to the metabolic remodeling accompanied by the altered secretion of cytokines, chemokines, and inflammatory mediators

Three forces converged to build it, each one expanding what the next could become

Hippocampal hyperactivity, therefore, increases excitatory input to the PFC and this increased tonic activity can lead to reductions in synaptic density [117]

T.GuptaS.SperkM.Svensson-AkusjarviS.et al