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Indeed, it has been demonstrated a role for IGF signaling in maintaining glomerular integrity, by preserving podocytes and the glomerular basement membrane from damage
Preventing Microbial Contamination Always use sterile techniques and solvents

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Brizuela L, Richardson A, Marsischky G, Labaer J (2002) The FLEXGene repository: exploiting the fruits of the genome projects by creating a needed resource to face the challenges of the post- genomic era

In addition, a potentially reduced off-target toxicity compared to the cleavable linker conjugates is expectable, as non-cleavable ADCs can provide greater stability and tolerability
