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A-syn and early synaptic dysfunction Evidence from both human and animal models has demonstrated that before clear signs of neurodegeneration appear in specific brain regions, other dysfunctions occur in the same neuronal circuits at a synaptic level in apparently intact cells

Khadimallah I, Jenni R, Cabungcal JH, Cleusix M, Fournier M, Klauser P, et al


The choice of route is based on considering the drugs pharmacokinetic properties, convenience of administration and patients health status (Brianna and Lee 2023

In research and some specialty settings, intestinal permeability can be assessed with methods such as orally ingested sugar probes like lactulose and mannitol, while some endoscopic or biopsy-based techniques are used more selectively

ClD and MS performed structural data analyses
