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The catalytic cysteine is highly susceptible to oxidation and nitrosylation, leading to reversible or irreversible modifications that abolish its nucleophilic function and inactivate its enzyme activity (87, 88)

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1.7%, respectively).[21] Despite the significant improvement, the inclusion of patients with varicocele in the study population may make it difficult to correctly interpret the effect of LC and LAC in men with idiopathic infertility