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Description
Melanin not only protects skin from harmful UV rays, it also is responsible for skin pigmentation
Its job is specific: it inhibits an enzyme called NNMT nicotinamide N-methyltransferase that becomes overactive in fat tissue, especially as we age
GFP-Trap agarose beads (gta-20) were supplied by ChromoTek, mouse anti-FLAG agarose (A2220) from Sigma-Aldrich, mouse anti-HA antibody bound to agarose clone HA.7 (A2095) from Sigma-Aldrich
To date, no clinical trials have been conducted in pSS patients
Neutrophil elastase appears to be a key marker
PubMed Central, GABA and Glycine
