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The primary endpoints that track response to MOTS-c therapy align with the peptide's core mechanisms: insulin sensitivity, mitochondrial function, body composition, and inflammatory tone
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While phosphorylation at Ser616 enhances fission activity, phosphorylation at Ser637 exerts an inhibitory effect under physiological conditions (Longo et al., 2021)

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Epub 2010 Feb 17 Waring RH, Ngong JM, Klovsra L, Green S, Sharp H: Biochemical Parameters in Autistic Children
