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After exposure to oxidative stimuli, Nrf2 dissociates from Keap1, its negative regulator, and translocates into the nucleus where it heterodimerizes with small Maf proteins [77] and binds to antioxidant responsive element (ARE) sequences, triggering a cytoprotective adaptative response
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FIGURE 2 Finally, BPC 157 administration cured the alkali burn-induced skin injury (Huang et al., 2015)

Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12) The improvement of the sleep-wake rhythm disorders appeared immediately after the administration of high doses (3,000 micrograms/day) of methylcobalamin

, Chen, P.S