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Goldin et al., When looking more specifically at pathologies affecting the brain, modulations of the glyoxalase system have been observed in aging as well as in various neuropathological conditions, including ischemia, epilepsy, Alzheimer's disease and Parkinson's disease (Ramasamy et al., 2005

Escribano BM, Colin-Gonzalez A, Santamaria A, Tunez I (2014) The role of melatonin in multiple sclerosis, Huntingtons disease and cerebral ischemia
(2022) found that MT scavenges ROS by repressing the expression of the senescence-related gene SlCV

These two receptor systems are synergistic simultaneous activation produces a larger GH pulse than either compound alone

Fulia, F
