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Mechanistically, selenium deficiency may exacerbate thyroid-related neurological dysfunction through three pathways: impaired deiodinase activity, weakened antioxidant defense, and disrupted selenium transport (134136)

Isatuximab (SAR650984) and Daratumumab are instead monoclonal antibodies that target CD38, which is also highly expressed on multiple myeloma (MM) cells

Table 4 illustrates the most predominant studies concerning mushrooms in intestinal epithelial homeostasis, health benefits, and gut microbiota regulation

Although it is not clear if DHEA modulates bioenergetic pathways in immune cells, it has been shown to attenuate LPS-induced production of pro-inflammatory mediators in murine RAW 264.7 macrophages (210)