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Women with known B12 deficiency should be monitored during pregnancy with appropriate blood tests, and treatment should be adjusted according to clinical response rather than targeting specific serum B12 levels

Table 1 Characteristics of study participants

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Detailed examination reveals megaloblastic anemia, decreased serum vitamin B12 levels, and Mild proteinuria is observed in more than half of patients with IGS (79).Neurological complications, protracted infections, failure to grow and thrive, and amblyopia may manifest as other possible clinical signs of cobalamin deficiency (10)

B12 is fundamental to a number of important metabolic processes, including: Red blood cell formation Nervous system function Nutrient absorption Adrenal gland support Cognitive function and memory Brain cell regeneration DNA synthesis Mitochondrial metabolism Male and female reproductive health Because of its important role in the nervous system, severe B12 depletion over time can lead to irreversible neurological damage

Published Research on AOD-9604 The following peer-reviewed studies are summarized below