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S1PR1 is mainly expressed in astrocytes, where it plays a key role in driving astrocyte-mediated neuroinflammation, thereby disrupting glutamatergic balance (Stockstill et al., 2018)

The renal risks of smoking: an update

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The biggest obstacle to the discovery of therapeutics for sepsis is its diverse etiology among patients (55), which have prompted researchers to study the molecular mechanism of sepsis progression based on systemic inflammatory responses

Accordingly, we can hypothesize that ferroptosis may serve to regulate normal epidermal differentiation during the pathophysiology of ichthyosis