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[DOI] [PubMed] [Google Scholar] 104.Ling S., Diao H., Lu G., Shi L

doi: 10.1038/ni.3818 149 RenauerPCoitPJeffriesMAMerrillJTMcCuneWJMaksimowicz-McKinnonKet al

Molecular dynamic investigations proposed that, in the process of ferroptosis, alterations in lipid composition cause changes in cellular membrane shape and curvature, leading to exposure to more oxidants, irreversible destruction to the membrane integrity, and ferroptotic cell death (Jaganjac et al., 2020)

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Thus, CSCs evade conventional therapies by sustaining their antioxidant environment