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Key functional nodes within the default mode network , which includes the hippocampus, amygdala, and medial prefrontal cortex, have been implicated in AD and epilepsy (287, 288)

PMCID: PMC2696075

Pour qu'elle soit en mesure de remplir toutes ses fonctions dans l'organisme, nous devons ingrer la vitamine B12 par le biais de notre alimentation

*Correspondence: Zhong-hong Yan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)

Rethinking B12 Deficiency and Supplementation In addition to redefining B12 deficiency, clinicians should consider supplementation in older patients with neurological symptoms even if their levels are within normal limits, she said