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In three of the studies included in this systematic review, supplementation doses of 1 to 3 g of l-C or GPL-C over a period of 4, 8, or 24 weeks did not observe significant differences in moderate-intensity exercise performance parameters [23,30,34]

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The discrepancies can be due to different design of the studies and also the duration of L-carnitine consumption, in such a way that it was on average 82 days in the Kitano and co-workers study, while in the present study it was consumed for 6 weeks (42 days) by almost 85% of patients