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Description

Ceramide analogs: D-threo-1-phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (P4) or a P4 derivative, like D-threo-4'-hydroxy-1-phenyl-2-palmitoylamino-3-pyrrolidino -1-propanol (4'-hydroxy-P4), D-threo-1-(3',4'-trimethylenedioxy)phenyl-2-palmitoylami no-3-pyrrolidino-1-propanol (trimethylenedioxy-P4), D-threo-1-(3',4'-methylenedioxy)phenyl-2-palmitoylamino- 3-pyrrolidino-1-propanol (methylenedioxy-P4) and D-threo-1-(3',4'-ethylenedioxy)phenyl-2-palmitoylamino-3 -pyrrolidino-1-propanol (ethylenedioxy-P4 or D-t-et-P4)

Hiertoe behoren: Obesitas (zwaarlijvigheid) Atherosclerose Diabetes Degeneratieve zenuwaandoeningen Vruchtbaarheidsstoornissen bij mannen Cataract Chronische ontstekingen (reuma, artritis etc.) Het biochemische werkingsprincipe van glutathion, namelijk de ontgifting van cellen en het wegvangen van vrije radicalen, geeft steeds vaker aanleiding om het tripeptide voor therapeutische doeleinden te gebruiken

Stimulate the production of hair melanin, regulate the energy metabolism of hair follicle cells, remove free radicals from skin, and inhibit the activity of 5-a reductase

Symmetry suggests no significant publication bias, whereas asymmetry may indicate potential bias, such as missing studies with nonsignificant results

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Jia Q., Han Y., Huang P., Woodward N.C., Gukasyan J., Kettunen J., Ala-Korpela M., Anufrieva O., Wang Q., Perola M., et al