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, In addition, there appears to be a gradient of free calcium that decreases from the posterior to the anterior ends of lens fiber cells

doi: 10.5603/FHC.a2014.0034

doi: 10.1016/S0140-6736(20)32466-1 305 LogunovDYDolzhikovaIVZubkovaOVTukhvatulinAIShcheblyakovDVDzharullaevaASet al

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This is significant because, if a single valid vector can be identified (see below for criteria), it demonstrates that somatic and affective symptoms have a common core and, hence, a shared pathophysiology [25]