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Contingency analyses were performed for qualitative variables, and the differences between groups were compared using 2 and Fishers exact tests

Using transcriptomic analysis, we find that activation of the p53p21 pathway down-regulates expression of many genes involved in nucleotide metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Davis H.E., McCorkell L., Vogel J.M., Topol E.J

There are many theories which are trying to explain the aging process, each from its own perspective, and none of the theories can explain all details of it

Finally, a subset of ZIPs localized to intracellular membranes, such as ZIP7 in the ER, and ZIP9, ZIP11 and ZIP13 in the Golgi and ER, support organelle-specific zinc signaling, although their precise subcompartmental localizations remain areas of active investigation

When these measurements are high, that's a sign of both impaired mitochondrial function as well as poor metabolism and absorption of amino acids