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People with a known cobalt allergy, typically identified by reactions to metal jewelry or implants, may occasionally react to vitamin B12 supplements because cobalt is a structural component of all cobalamins

Heald AH, Kaushal K, Siddals KW, Rudenski AS, Anderson SG, Gibson JM

While an oral supplement may work for some people, individuals with these conditions cannot properly absorb vitamin B12 and can benefit from vitamin B12 injections

The informed consent challenge compounds the problem

A randomized placebo-controlled trial in 452 elderly participants requiring leg surgery due to a fracture found 1 gram of omega-3 fatty acids, taken for 30 days following surgery, reduced the risks of DVT and pulmonary embolism without increasing bleeding events or other complications

As B12 plays an essential role in enhancing the metabolic function of the cells, this nutrient can boost energy release, improve memory and help prevent heart disease