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We calculated polygenic scores from genome-wide association studies (GWAS) for 127 traits and diseases, and used these to discover molecular correlates of polygenic risk (e.g., genetic risk for inflammatory bowel disease was negatively correlated with plasma cystine)
ASCT2 exhibits a notably higher affinity for Gln compared with that of other neutral amino acids, underscoring its importance as one of the most critical transporters for Gln [17]

S., Patel K., Muldoon-Jacobs K., et al
Although direct clinical investigations specifically addressing SGLT2 inhibitor-polyphenol interactions remain scarce, accumulating theoretical frameworks and preliminary experimental observations warrant clinical vigilance

During the experiments, animal welfare was monitored daily