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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Tsunada S, Iwakiri R, Fujimoto K, Aw TY

i.p, Intraperitoneal perfusion

If aliquoting is required, use sterile containers and validated storage conditions

The hypothesis that these reactive intermediates are responsible for cell death is supported by the observation that a cell line selected for erastin resistance showed several-hundred-fold upregulation of AKR1C family genes (Dixon et al., 2014), which encode aldoketoreductases that, among other functions, reduce reactive end-products of lipid peroxidation to unreactive compounds (MacLeod et al., 2009)

Ann N Y Acad Sci 1031:249262

H., Li, C., Lin, J
