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Mitochondrial and energy-pathway models: Exploring how ERR activation correlates with mitochondrial-associated transcriptional signatures and cellular energy-demand responses in controlled experimental conditions

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The primary outcome measure was safety, and key secondary outcomes were mean change from baseline best- corrected visual acuity (BCVA), mean change from baseline macular sensitivity measured by microperimetry, change from baseline in ellipsoid zone width at weeks 12 and 24, and NAC levels in the aqueous humor and in plasma

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