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The combination of the amylin analogue pramlintide and the recombinant human leptin metreleptin caused significant weight reductions ( - 11.5kg) in comparison with monotherapy in a 24-week phase 2 clinical trial [248]

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It has biological relevance to tissue remodeling

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Once type 2 diabetes has been established, medication may aid in maintaining health by reducing exposure to CVD risk factors (CVD)
