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Loss of Unc5B decreases BBB Wnt/catenin signaling, and -catenin overexpression rescues Unc5B mutant BBB defects

Public MS data used in this work are as follows: PXD006637 (mouse brain DDA) 29 , PXD019113 (Vero E6 DIA) 8 , PXD013453 (yeast R2P2) 6 , PXD014525 (RPE1, two-proteome) 3 , PXD017476 (U2OS) 9 , PXD009227 (U-87 DDA) 1 , PXD019797 (human synthetic phosphopeptide dataset) 27 , PXD004573 (yeast synthetic phosphopeptide dataset) 28

Lamers, C

The compound's primary mechanism

Usdin TB, Mezey E, Button DC, et al

Researchers have reported a variety of biomimetic nanomedicines by engineering whole cells for synthesis of whole-cell-based systems, and parts of cells for semi-biological biomimetic systems