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A multifaceted role for polyamines in bacterial pathogens

But before you roll up your sleeves, it's essential to understand the ins and outs of B12 shots, including whether or not you need a prescription to get them

doi: 10.1089/ars.2012.5149 143 MiyakeM.OdaY.OwariT.IidaK.OhnishiS.FujiiT.et al

As GSTP1 knockdown significantly increased cisplatin and carboplatin chemosensitivity in A2780 cells, we further investigated whether GSTP1 knockdown in the related platinum-resistant A2780DPP cell line (Behrens et al, 1987) could re-sensitise these drug-resistant cells to platinum-based chemotherapy

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As IRE1 is the most evolutionarily conserved UPR sensor, we investigated whether it also determines ferroptosis sensitivity in lower organisms