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Researchers should add one compound at a time, assess tolerance, and avoid the temptation to implement complex protocols immediately

Elevated serum B12 levels often indicate underlying conditions such as haematological disorders, liver disease, or renal impairment rather than toxicity from supplementation

Reference: Azuri J, Hammerman A, Aboalhasan E, et al

Baseline Health Assessment : Including cardiovascular evaluation, metabolic panel, and hormone level assessment to establish pre-study baselines

Injectable/IV NAD+ is not FDA-approved (or approved by any major regulator) for energy, metabolic or longevity uses, and its safety and efficacy for these uses are not established presented for research and educational use only