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Underlying Causes: The specific pathogenesis can vary based on the underlying cause of B12 deficiency: Dietary deficiency: Inadequate intake of B12, common in vegans and vegetarians

Myelin Synthesis : Vitamin B12 is a cofactor for the enzyme methionine synthase, which is involved in the conversion of homocysteine to methionine

Keep it away from the freezer compartment and the door shelves, which experience the most temperature fluctuation

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In trials that added it to injected insulin, basal insulin requirements fell roughly 60% to 80% while control improved

Vitamin B6 is another crucial cofactor for transsulphuration of homocysteine to cystathionine (2)