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Because of these uncertainties, the evidence supporting a generalized use of NAC to prevent CIN is currently considered insufficient [178]

PLOS ONE 7 , e49555 (2012)

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Shokrpour, M

This is because sulfur based amino acids are foundational components of many enzymes, including the powerful antioxidant enzyme glutathione

First, the direct interaction between GSH and the active site of tyrosinase, resulting in the activation of tyrosinase activity when the concentrations of GSH is below 3 mM and inhibition at higher GSH concentrations [82]