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Mutated IDH 1 and 2 have been found in ~20% of AMLs and thus constitute another therapeutic target of interest [118]
Zahid S, Khan R, Oellerich M, Ahmed N, Asif AR
demonstrated that curcumin induced G2/M cell cycle arrest and non-apoptotic autophagy in U87-MG and U373-MG cells [399]
In response to primary inflammatory stimuli, such as those mediated by TNF, IL-1, and TLR agonists, several cell types produce the glycoprotein pentraxin 3 (PTX3) 71
Transplantation of the modified HSPCs seemed to correct for haemophilia A, evidenced by the large reduction in bleeding in the mice receiving gene therapy
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