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an Interventional Pre-Post Study

Some practitioners prefer rotating between local and systemic sites

It is a case of correlation in a multi-treatment protocol being misattributed to a single component

By week 6 of a daily or every-other-day protocol, absorption from scarred injection sites can drop by 1525% compared to baseline

In regard to DPI, we previously demonstrated that low micromolar concentrations effectively reduced tumor growth and metastasis in a MYCN-driven zebrafish model of NB, with low associated toxicity ( A limitation of this study is the discrepancy between the strong in vitro synergy of the MitoQ + DPI combination and its limited effectiveness in in vivo models of NB

The preclinical evidence is robust, consistent, and mechanistically plausible, but the gap between rat sciatic nerve transection models and human diabetic neuropathy is significant