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Overall, renal Oat1 expression is androgen-regulated, renal Oat2 expression is modulated by female GH secretion pattern, and hepatic Oat3 expression is influenced by both androgens and female GH secretion pattern (Buist et al., 2003)

Journal of Alzheimer's disease : JAD, 62(2), 561570

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It gains its effectiveness from both its ability to bind with copper and its ability to up and down-regulate a minimum of 4,000 different genes

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