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The reason for this is also intermicellar interactions 36

Daz-Angulo S, Lpez-Hoyos M, Muoz-Cacho P, Lpez-Escobar M, Gonzlez-Lpez MA

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

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In assessing responses to metal stress, future research should exploit these systems to elucidate the output of the integrated GSH concept i.e

We propose that cytosolic proteotoxic stress due to defective protein folding is associated with mild, but chronic reduction of mitochondrial protein import and impaired mitochondrial function in aneuploid cells
